Indian Journal of Obstetrics and Gynecology Research

Print ISSN: 2394-2746

Online ISSN: 2394-2754


Indian Journal of Obstetrics and Gynecology Research (IJOGR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific more...

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Supriya, Verma, and Verma: Ovarian cyst mimicking acute appendicitis in pregnancy: A case report


Ovarian cysts, also known as ovarian masses or adnexal masses are fluid filled sacs or pockets in an ovary or on its surface. These are found incidentally in asymptomatic women. Ovarian cysts can be physiologic (during ovulation) or neoplastic. It can be benign, borderline (low malignant potential) or malignant.

Ovarian cysts are considered large in size when they are over 5 cm and giant when they are over 15 cm. Right lower quadrant pain is the main presentation of an ovarian cyst.

Acute appendicitis is the most common surgical problem in pregnancy requiring emergent intervention.1

The worldwide incidence of acute appendicitis in pregnancy is 1 out of 1500 pregnancies.2 Pregnancy is associated with anatomic and physiologic changes that may disguise and delay the diagnosis of acute appendicitis. Antibiotic treatment does not always improve the outcome and emergency intervention is required. Early diagnosis and surgical intervention is mandatory for the eventful outcome of pregnancy.1

Case Report

A 29-year old female patient was referred from a local hospital with the complaints of amenorrhea for 5 months and pain in right side of the lower abdomen for 2 days. At the time of presentation, following were her vitals:

(Pulse rate = 108/min, Blood pressure = 104/68 mm of Hg, Respiratory rate = 20/min). She was found to be afebrile. There was no history of anorexia or vomiting. Nausea was present. There was no history of similar complaints in past.

On per abdominal examination, there was a tenderness present in right iliac fossa (RIF). Rebound tenderness was also present. Ultrasonography(USG) of the abdomen done at the local hospital showed a well defined non compressible tubular structure approximately 3.2 X7.5 cm in RIF. Probe tenderness was also found. So, a suspicion of acute appendicitis was kept and the patient was referred to our hospital. The patient was further investigated. USG abdomen was repeated in which appendix could not be visualised in RIF. Single live intrauterine fetus was found in uterus with fetal heart rate of 149/min. Complete haemogram was done in which the patient had mildly elevated total leucocyte count with a predominance of neutrophils (85%). Liver and kidney function tests were found to be normal. Routine urine examination was within normal limit. Serum electrolytes were within normal limit. The patients Alvarado score was calculated to be 7 out of 10. A diagnosis of acute appendicitis was made and emergency appendectomy was planned.

Intra operative findings

Mcburneys grid iron incision was given. On opening of the peritoneal cavity, a large ovarian cyst of size 10X 8 cm was found in RIF. Appendix was found to be normal. There was mild serosal oedema. It was lying adherent to the cyst. During manipulation of the cyst, it accidentally got ruptured. Chocolate coloured contents were present inside the cyst. About 50-60 ml of chocolate coloured fluid was drained and appendectomy was done. Post operative period and recovery of the patient was uneventful and she was discharged on 2nd postoperative day.

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The incidence of appendicitis in pregnancy (0.05–0.07%) is similar to that in the general population.3 Acute appendicitis is not rare in the first trimester of pregnancy. 50% cases of appendicitis in pregnancy occur in the 2nd trimester. It accounts for almost 50% of all pregnancy-related appendicitides.4

Appendicitis is difficult to diagnose in pregnancy, since the clinical presentation often varies and diagnosis is usually delayed. Right-side abdominal pain is the principal basis for diagnosis. Lower quadrant pain in 2nd trimester, produced by the traction on the suspensory ligament is common and can mimic the appendicitis.

Leucocytosis and low-level fever, as in the non-pregnant state, are unreliable for diagnosis since mild physiological leucocytosis of pregnancy is a normal finding.

Pregnant patients are more likely to present with perforations probably due to the immunosuppression in pregnancy (43%).5, 6, 7

USG abdomen has a sensitivity of 78% and a specificity of 83% for the diagnosis of appendicitis in pregnancy. If ultrasonographic findings are equivocal – MRI without gadolinium contrast can be preferred. It has a high sensitivity and specificity (91.8%,97.9% respectively) for the diagnosis of clinically suspected acute appendicitis in pregnant patients.8

Negative appendectomy rate in pregnancy varies as follows: Clinical assessment alone has a negative appendectomy rate of 54% while clinical assessment when combined with USG has a negative appendectomy rate of 32%. Clinical assessment when combined with CT, markedly reduces the negative appendectomy rate upto 8%.8

Gynaecological disorders like large ovarian cysts or its rupture, haemorrhage or torsion, tubo-ovarian abscess, pelvic inflammatory disease, endometriosis, ectopic pregnancy, salpingitis and fibromyoma uteri have their clinical presentation as right lower quadrant pain and often mimic appendicitis. Hence, when appendicitis is suspected, timely obstetric as well as general surgical consult is essential. This can significantly reduce the chance of negative appendectomy.

However, delay in confirming diagnosis may contribute to high perforation rate. Delaying surgery may increase the mortality rate to 4% while fetal death occurs in almost 43% of perforated appendicitis.9

Improved laparoscopic technique has shown some advantages over open laparotomy, like decreased postoperative pain, reduced hospital stay, and wound complications.10 Postoperatively, early mobilization is advantageous for the prevention of thromboembolism as deep vein thrombosis is higher in pregnancy.11


Although imprecise and often not accurate, history and physical examination continue to be the best way to diagnose appendicitis in pregnancy. However, when it is suspected, prior and prompt obstetric as well as general surgical consultation should be considered.

Conflicts of Interest


Source of Funding




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© This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Article type

Case Report

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Authors Details

Supriya, Vijay Verma*, Ravi Verma

Article History

Received : 15-01-2020

Accepted : 25-03-2021

Available online : 25-08-2021

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