Indian Journal of Obstetrics and Gynecology Research

Print ISSN: 2394-2746

Online ISSN: 2394-2754


Indian Journal of Obstetrics and Gynecology Research (IJOGR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific more...

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Bhavana Gupta*

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Molar pregnancy with false negative urine pregnancy test, the hook effect

Case Report

Author Details : Bhavana Gupta*

Volume : 8, Issue : 1, Year : 2021

Article Page : 133-135

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Molar pregnancy is characterized by high level of serum b hcg which can be usually detected by urine pregnancy test as a first screening test. Urine pregnancy test is also used as the first screening test for patients of reproductive age presenting with gynecological problem in order to exclude pregnancy. Rarely large amounts of b human chorionic gonadotrophin (hcg) may cause a false negative result due to over saturation of the assay system, known as, ‘the hook effect’. This can result clinical dilemma in the diagnosis and delay in the management. When there is clinical features of molar pregnancy, the knowledge of “The Hook Effect” will help at arriving at the diagnosis.

Keywords: β hCG(serum β -human chorionic gonadotropin, Hook effect, Molar pregnancy, Urine pregnancy test.

How to cite : Gupta B , Molar pregnancy with false negative urine pregnancy test, the hook effect. Indian J Obstet Gynecol Res 2021;8(1):133-135

Copyright © 2021 by author(s) and Indian J Obstet Gynecol Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (