Indian Journal of Obstetrics and Gynecology Research

Print ISSN: 2394-2746

Online ISSN: 2394-2754


Indian Journal of Obstetrics and Gynecology Research (IJOGR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...

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V Arunadevi*, S N S Minnalkodi

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Dienogest treatment improves quality of life in women with endometriosis: A prospective cohort study

Original Article

Author Details : V Arunadevi*, S N S Minnalkodi

Volume : 7, Issue : 3, Year : 2020

Article Page : 348-351

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Background: One of the chronic disabling illness affecting approximately 10% of women in midst of their
reproductive period is Endometriosis. The treatment goal of endometriosis is to activate decidualization
within the hormonally dependent ectopic endometrium and is regularly given to alleviate pain symptoms
and reduce its recurrence among women.
Objectives: The aim of the study was to evaluate the effectiveness of dienogest in reducing pain and its
influence on (QOL) quality of life among women affected with endometriosis.
Materials and Methods: A prospective observational cohort study was conducted at Karpaga Vinayaga
Institute of Medical Sciences and Research Centre including fifty patients with endometriosis treated with
dienogest two mg per day for three months.We assessed the pelvic pain symptoms by visual analogue scale
and (QOL)quality of life was determined by physical and mental index before and after 3 months of use of
Study Design: To perform statistical analysis, we used paired t test.
Results: Women were on average 33.18 + 4.43 years. The mean +SD of VAS of 7.72 (0.73) in women
with endometriosis was progressively decreased to 4.34(0.66) after 3 months of treatment with dienogest.
The physical index score values increased significantly from 31.94 to 42.77 (p<0> increased from 35.07 to 45.86 (p<0> acne, hot flushes and weight gain.
Conclusion: The results suggest that among women with endometriosis, dienogest has a relatively
favorable safety profile and is well accepted in bettering the quality of life (QOL).

Keywords: Endometriosis, (QOL) Quality of life, Dienogest, Pelvic pain.

How to cite : Arunadevi V , Minnalkodi S N S , Dienogest treatment improves quality of life in women with endometriosis: A prospective cohort study. Indian J Obstet Gynecol Res 2020;7(3):348-351

Copyright © 2020 by author(s) and Indian J Obstet Gynecol Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (

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